They would probably have to nerf inferno for a console version. I can't see the controller being as smooth as a mouse and board in terms of controls for this game. Alot of the skills require aiming which would require use of both analog sticks. The "pointing" control would be sloppy, but the movement and skill slots would be smooth. The aiming is extremely important though.
What you say is true and i agree to an extent. That said, i think that the PC version of Torchlight transitioned pretty well to the Xbox 360. I'm sure similar issues arose with the aiming. That would make it difficult but not impossible.
@ecs33 Blizz could also recommend that players use a usb keyboard and mouse to play the game, and make the controls like they were for D1 on PS1. People would go for the keyboard/mouse combo for sure.